Prevalence of Cytological and Histological Cervical Uterine Abnormalities in a Group of Women in Bogotá, Colombia
Keywords:
Cervical intraepithelial neoplasia, prevalence, epidemiology, mass screeningAbstract
Objective: To describe the prevalence of cytological abnormalities and neoplasias in a group of women from Bogotá, Colombia.
Methods: A descriptive analysis was done among women attended health services in a low-resource area of Bogotá. All women had history of sexual onset, aged 25 to 59 years, and were investigated with conventional cytology.
Results: 4,957 cases were analyzed. The average age was 39.2 years. In total 69.1% of pap smears were negative, 24.7% reported ASC-US, 4.3% LSIL, 1.2% HSIL, and 0.1% invasive cancer. 762 biopsies were done (48.29% negative and 49,08% neoplasic changes). The global prevalence of intraepithelial neoplasias and carcinoma was 7.54%. The prevalence of CIN 2 and CIN 3 was 1.3% (0.4% y 0.9%). Two invasive carcinomas were detected (0.04%).
Conclusions: The prevalence of cytological abnormalities was unusually high. Histological abnormalities were investigated through three different screening methods representing highly reliable data. The prevalence of HSIL (CIN II and CIN III) and invasive cancer observed is higher than previous reports from other countries.
Author Biographies
Mauricio González, Instituto Nacional de Cancerología
Grupo de Investigación Clínica, Instituto Nacional de Cancerología. Bogotá, Colombia.
Raúl Murillo, Instituto Nacional de Cancerología
Subdirección de Investigaciones, Vigilancia Epidemiológica, Promoción y Prevención, Instituto Nacional de Cancerología. Bogotá, Colombia.
Elkin Osorio, Secretaría Distrital de Salud
Laboratorio de Salud Pública, Secretaría Distrital de Salud. Bogotá, Colombia.
Óscar Gamboa, Instituto Nacional de Cancerología
Subdirección de Investigaciones, Vigilancia Epidemiológica, Promoción y Prevención, Instituto Nacional de Cancerología. Bogotá, Colombia.
Jaime Ardila, Instituto Nacional de Cancerología
Subdirección de Investigaciones, Vigilancia Epidemiológica, Promoción y Prevención, Instituto Nacional de Cancerología. Bogotá, Colombia.
References
Murillo R, Piñeros M, Hernández G. Atlas de mortalidad por cáncer en Colombia. Bogotá: Instituto Nacional de Cancerología-Instituto Geográfico Agustín Codazzi; 2004.
Piñeros M, Cendales R, Murillo R, Wiesner C, Tovar S. Cobertura de la citología de cuello uterino y factores relacionados en Colombia, 2005. Rev Salud Pública. 2007;9(3):327-41.
https://doi.org/10.1590/S0124-00642007000300002
Murillo R, Almonte M, Pereira A, Ferrer E, Gamboa OA, Jerónimo J, et al. Cervical cancer screening programs in Latin America and the Caribbean. Vaccine. 2008;26(Suppl.11):L37-48.
https://doi.org/10.1016/j.vaccine.2008.06.013
Mora M. Guía técnica para laboratorio de citología. Bogotá: Secretaría Distrital de Salud de Bogotá; 2007.
Sankaranarayanan R, Wesley R. A practical manual on visual screening for cervical neoplasia. IARC Technical Publication. No. 41. Lyon: IARC; 2003.
Sellors JW, Sankaranarayanan R. Colposcopy and treatment of cervical intraepithelial neoplasia: A beginners manual. Lyon: IARC; 2003.
Ferris DG, Greenberg MD. Reid's Colposcopic Index. J Fam Pract. 1994;39(1):65-70.
WHO. Histological classification of tumours of the uterine cervix [Internet]. Lyon: International Agency for Research on Cancer. [Citado 2009 abr 16]. Disponible en: http://screening.iarc.fr/atlasclassifwho.php.
Grisales H, Vanegas A, Gaviria A, Castaño J, Mora M, Borrero M, et al. Prevalencia de anormalidades de células epiteliales y factores asociados en mujeres de un municipio rural colombiano. Biomédica. 2008;28(2):271-83.
https://doi.org/10.7705/biomedica.v28i2.98
Bravo M, Erazo J, Álvarez A, Casas M, Ortiz O, Álvarez-Soler J. Prevalencia de anormalidades en la citología cervical en tres grupos poblacionales de mujeres en Popayán Colombia 2003-2005. Rev Colomb Obstet Ginecol. 2008;59(3):190-8.
Gupta S, Sodhani P, Halder K, Chachra KL, Sardana S, Singh V, et al. Spectrum of epithelial cell abnormalities of uterine cervix in a cervical cancer screening program: Implications for resource limited settings. Eur J Obstet Gynecol Reprod Biol. 2007;134(2):238-42.
https://doi.org/10.1016/j.ejogrb.2006.07.022
Anorlu RI, Abdul-Kareem FB, Abudu OO, Oyekan TO. Cervical cytology in an urban population in Lagos, Nigeria. J Obstet Gynaecol. 2003;23(3):285-8.
https://doi.org/10.1080/01443610310000100114
Kanno MB, Nguyen RH, Lee EM, Zenilman JM, Erbelding EJ. The prevalence of abnormal cervical cytology in a sexually transmitted diseases clinic. Int J STD & AIDS. 2005; 16(8):549-52.
https://doi.org/10.1258/0956462054679160
Universidad del Valle. Registro Poblacional de Cáncer de Cali. [Internet]. Cali: Universidad Del Valle. [Citado 2009 Oct 05]. Disponible en: http://rpcc.univalle.edu.co/es/SitiosEspecificos/pdf-sitiosespecificos/Sitios_Especificos.php?sitio=10.
Muñoz N, Méndez F, Posso H, Molano M, van den Brule AJ, Ronderos M, et al. Incidence, duration, and determinants of cervical human papillomavirus infection in a cohort of Colombian women with normal cytological results. J Infect Dis. 2004;190(12):2077-87.
How to Cite
Downloads
Downloads
Published
Issue
Section
License
Todos los derechos reservados.
Article metrics | |
---|---|
Abstract views | |
Galley vies | |
PDF Views | |
HTML views | |
Other views |