Experience with Cutaneous Lymphomas between January 1995 and April 2008 at the National Cancer Institute
Keywords:
Lymphoma, Lymphoma Non-Hodking, Mycosis FungoidesAbstract
Objectives: To describe different cutaneous lymphomas in accordance with WHO-EORTC classification under observation at the National Cancer Institute (NCI) between January 1, 1995 and April, 2008.
Methods: A descriptive, retrospective study was carried out which included patients diagnosed with cutaneous lymphoma at the NCI from January 1995 until April 2008. Clinical cases were taken from Pathology Department data base. Statistical analysis was performed with Epi 2008 info program.
Results: A total of 252 case histories were reviewed, and 160 patients were included in the study: 139 T-cell lymphomas (87%) and 21 B-cell lymphomas (13%). The most common (63% of cases) was mycosis fungoides (MF). Among the variations of MF described, the frequency of hypopigmented MF (13%) stood out. The lymphoproliferative CD30+ disease group was the second most frequent among T-cell lymphomas. In the B-cell lymphoma group, the indolent lymphomas with excellent prognosis made up 5% of cases.
Conclusions: Primary cutaneous lymphomas are rare tumors. T-cell lymphomas predominate over B-cell. Most cases are low grade lymphomas and should be treated with skin therapies. Within each category, lymphomas exist that will progress and compromise internal organs.
Author Biographies
Xavier Rueda, Instituto Nacional de Cancerología
Clínica de Piel, Instituto Nacional de Cancerología, Bogotá D.C., Colombia
Carolina Cortés, Universidad Nacional de Colombia
Universidad Nacional de Colombia, Bogotá D.C., Colombia
Álvaro Acosta, Instituto Nacional de Cancerología
Clínica de Piel, Instituto Nacional de Cancerología, Bogotá D.C., Colombia
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