Gastrointestinal stromal tumors in the Hospital Universitario del Caribe, Cartagena de Indias, Colombia, 2009‐2011. A case series
Keywords:
Gastrointestinal neoplasia, Gastrointestinal stromal tumor, GISTAbstract
Gastrointestinal stromal tumors (GIST) are uncommon. they are neoplasms of interstitial cells of Cajal, mainly due to receptor mutations Cd117 (c-Kit), with their diagnosis being confirmed by immunohistochemical methods, and for which there are specific inhibitors (imatinib, sunitinib). We describe the clinical features, diagnosis, treatment, and follow-up of 6 cases (1 esophageal, two gastric, one duodenal, one jejunal and one colon), of which 4 were women, with an age range between 38 and 78 years (mean: 52). the signs and symptoms of each case are presented (anemic syndrome, abdominal pain and mass, etc.), as well as the operating characteristics of the imaging and endoscopic tests, and the histopathology. Minimally invasive resection was performed in 2 patients, 1 synchronous with colorectal adenocarcinoma and 2 cases of recurrence. The findings are consistent with the literature. There are controversies in prognosis, and medical expertise is limited by the low frequency, therefore, more evidence is needed about this disease.
Author Biographies
Eusebio Contreras, Universidad de Cartagena
Estudiante de Medicina, Universidad de Cartagena, Cartagena, Colombia
Haroldo Estrada, Universidad de Cartagena
Médico especialista en Oncología Clínica. Docente, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia
Estebana Benedetti
Médica especialista en Patología, Cartagena, Colombia
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