Leiomyosarcoma ovarian cancer: a rare tumour with aggressive behaviour
Keywords:
Leiomyosarcoma, Myocytes, OvarianAbstract
Leiomyosarcomas may originate in most of the organs developed outside the central nervous system. There are documented cases of leiomyosarcomas of intestinal, mesenteric, uterine, retroperitoneal, and of soft and vascular tissue origin. However, cases of primary ovarian leiomyosarcoma are extremely rare, with few cases reported in the international literature. Leiomyosarcomas are believed to be those that originate from the walls of existing vasculature in ovarian parenchyma, in the smooth muscle around the follicles, or from remnants of the Wolff duct. Most cases occur in post-menopausal patients, and have an unfavourable prognosis in the short term. The mainstay of treatment remains the complete tumour debulking, with negative surgical margins in order to reduce the potential for recurrence. The benefit of the use of adjuvant chemotherapy as part of treatment of this condition remains uncertain.
Author Biographies
Julian Yañez, Hospital Universitario Erasmo Meoz
Clínica Ginecología Oncológica, Hospital Universitario Erasmo Meoz, Cúcuta, Colombia
Angélica Duque, Instituto Nacional de Cancerología
Clínica Ginecología Oncológica, Instituto Nacional de Cancerología, Universidad Militar Nueva Granada, Bogotá D. C., Colombia
María Islena Beltrán, Instituto Nacional de Cancerología
Patología Oncológica, Instituto Nacional de cancerología, Bogotá D. C., Colombia
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