Resection of a rectal gastrointestinal stromal tumour by transanal minimally invasive surgery (TAMIS) after neoadjuvant treatment with Imatinib
Keywords:
Rectal GIST, Neoadjuvant, TAMIS, ImatinibAbstract
The primary treatment of choice for patients with a localised gastro-intestinal stromal tumour (GIST) is complete surgical excision with negative microscopic margins. However, in a space as small as that of the pelvis, complete resection of a large rectal tumour is difficult, and sometimes requires an abdominoperineal amputation. In order to reduce the size of the tumour, as well as the morbidity associated with more aggressive surgical procedures, neoadjuvant treatment with Imatinib was introduced in this case, with the response being monitored by of endoscopic ultrasound. The response obtained by reducing the tumour volume modified the strategy, making it possible to obtain a satisfactory resection using transanal minimally invasive surgery (TAMIS), preserving the anal sphincters and avoiding the genitourinary morbidity associated with the mesorectal excision.
Author Biographies
Fernando Fernández López, Hospital Clínico Universitario de Santiago
Unidad de Coloproctología, Servicio de Cirugía General y Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, La Coruña España
María Jesús Ladra Gonzáles, Hospital Clínico Universitario de Santiago
Unidad de Coloproctología, Servicio de Cirugía General y Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, La Coruña España
Francisco González Rodríguez, Hospital Clínico Universitario de Santiago
Servicio de Cirugía General y Digestiva, Hospital Clínico Universitario de Santiago, Santiago de Compostela, La Coruña España
Manuel Paz Novoa, Hospital Clínico Universitario de Santiago
Unidad de Coloproctología, Servicio de Cirugía General y Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, La Coruña España
Jesús Paredes Cotoré, Hospital Clínico Universitario de Santiago
Unidad de Coloproctología, Servicio de Cirugía General y Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, La Coruña, España
Manuel Bustamante Montalvo, Hospital Clínico Universitario de Santiago
Jefe de Servicio de Cirugía General y Digestiva, Hospital Clínico Universitario de Santiago, Santiago de Compostela, La Coruña, España
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