Primary splenic diffuse large B-cell lymphoma double hit: A subtype of poor prognosis
Keywords:
Non-Hodgkin Lymphoma, MYC gen, Double hitAbstract
Diffuse Large-cell Lymphoma B (DLCLB) is the most common type of lymphoma, constituting 35% of all cases of Non-Hodgkin’s Lymphoma (NHL). Primary Splenic Non-Hodgkin Lymphoma (PS-NHL) has an incidence of less than 1% of all lymphomas. The ‘‘double hit’’ lymphomas are related to the rearrangement of the MYC gene associated with another molecular alteration.
Author Biographies
Álvaro Martínez Manzano, Hospital General Universitario Santa Lucía
Servicio de Cirugía General y del Aparato Digestivo, Hospital General Universitario Santa Lucía, Cartagena, España
María Dolores Balsalobre Salmerón, Hospital General Universitario Santa Lucía
Servicio de Cirugía General y del Aparato Digestivo, Hospital General Universitario Santa Lucía, Cartagena, España
María Aránzazu García López, Hospital General Universitario Santa Lucía
Servicio de Cirugía General y del Aparato Digestivo, Hospital General Universitario Santa Lucía, Cartagena, España
References
Lymphoid neoplasms. In: American Joint Committee on Cancer. 6 th ed. New York, NY: Springer; 2002: 393-406.
https://doi.org/10.1007/978-1-4757-3656-4_48
Esparcia A, Roig P, Ca˜nizares R, Martínez C. Linfoma no Hodgkin esplénico. Aportación de un nuevo caso y revisión de la literatura. Rev Clin Esp. 2001;201:494-5.
https://doi.org/10.1016/S0014-2565(01)70894-6
Mu˜noz Hinojosa J, Baldin A, Quirarte C, Ávila G, Mu˜noz Gutiérrez J, Videl V. Linfoma no-Hodgkin primario de bazo y su manejo laparoscópico. Rev Mex Cir Endoscop. 2013;14:196-9.
Delgado Sánchez MJ, Bernardos Rodríguez A, Serrano Díez- Canedo J, Buezas Martínez G, Del Álamo Juzgado C. Fístula gastroesplénica por linfoma esplénico primario. Rev Esp Digest. 1994;86:543-5.
Connors JM. Non-Hodgkin lymphoma: the clinician's perspective-a view from the receiving end. Mod Path. 2013;26:S111-8.
How to Cite
Downloads
Downloads
Published
Issue
Section
License
Todos los derechos reservados.
Article metrics | |
---|---|
Abstract views | |
Galley vies | |
PDF Views | |
HTML views | |
Other views |